Thirteen-times European champions Real, who had come through each of their last three Champions League semi-final ties, had been second best for much last week's first leg which ended 1-1.
Valencia forward Carlos Soler scored a hat-trick of penalties as his side beat La Liga champions Real Madrid 4-1 at home in an extraordinary match on Sunday.
Barca feel familiar February blues as tiredness sets in
Images from the UEFA Champions League group matches played on Tuesday night
Madrid were not at their best but moved three points clear of rivals Barcelona.
Chelsea a 1-0 win over Manchester United in a compelling Premier League clash on Sunday
Barcelona forward Luis Suarez scored a hat-trick as his side thrashed arch-rivals Real Madrid 5-1 on Sunday in a highly entertaining 'Clasico' which surely will signal the end of hapless coach Julen Lopetegui's spell in charge of Real.
It was the third game in a row in which Real had broken the deadlock thanks to a penalty and they sealed the win when Benzema turned provider and allowed Marco Asensio to tap into an empty net early in the second half.
Eva Carneiro set to lose place on bench after Mourinho criticism
FA Cup winners Arsenal beat champions Chelsea 1-0 in England's Community Shield season curtain-raiser at Wembley on Sunday to end a long wait for victory over their London rivals.
Chelsea have signed Stoke City's Bosnian international goalkeeper Asmir Begovic on a four-year contract, the Premier League champions confirmed on Monday.
Marouane Fellaini played chief tormentor as France suffered a 4-3 home defeat in a home friendly against Belgium on Sunday.
Chelsea boss Jose Mourinho has no plans to let any of his English Premier League title-winning squad depart Stamford Bridge in the close season.
Jose Mourinho will receive a third Premier League winners' medal on Sunday but the Chelsea manager is not feeling so charitable this time .
Belgium's soccer team received a hero's welcome in Brussels on Sunday, after achieving their best-ever World Cup result in Russia.
Belgium under-21 international Gregory Mertens died on Thursday, three days after collapsing with heart failure during a match, a spokesman for his club, Lokeren, said.
Paris St Germain substitute Edinson Cavani, criticised by French media lacking composure in front of goal, responded in style to earn a 2-1 home win over Chelsea in their Champions League last-16 first leg on Tuesday.
Holders Real Madrid breezed past Chelsea into the semi-finals of the Champions League with Rodrygo's double securing a 2-0 win at Stamford Bridge.
Renault's Chinese test driver Guanyu Zhou won a virtual Bahrain Grand Prix on Sunday as Formula One sought to entertain fans with esports action in a season stalled by the spreading coronavirus. The first seven rounds of the real championship have been cancelled or postponed, including the showcase Monaco Grand Prix, and it remains to be seen how many there will be ultimately.
Chelsea wrapped up their pre-season tour of the United States on a high note by beating Barcelona in a shootout after their International Champions Cup match ended 2-2 on Tuesday.
Chelsea reached the League Cup final after Branislav Ivanovic's towering extra-time header secured a 1-0 victory over Liverpool in a rip-roaring semi-final second leg at an electric Stamford Bridge on Tuesday.
Frank Lampard, Chelsea's all-time leading scorer, netted against his old club when he came on as a late substitute for Manchester City to give the champions a 1-1 draw.
Daryl Janmaat, Gerard Deulofeu and Roberto Pereyra all scored late on in response to Eden Hazard dragging Chelsea back into the game with a curler in the 82nd minute after Tiemoue Bakayoko was sent off for a second booking on the half-hour.
Much-fancied Belgium fought back from a goal down to score twice in the final 20 minutes and earn a hard-fought 2-1 victory over gutsy Algeria in their World Cup Group H opener on Tuesday.
Schalke 04 halted the Chelsea juggernaut when they drew 1-1 in their Champions League Group G opener at Stamford Bridge on Wednesday, handing a wake-up call to the London club who had won their first four games of the season.
Sadio Mane scored twice to help Senegal fight back and shock Brazil 4-2 in a friendly in Lisbon on Tuesday.
The European champions, who were humbled 3-0 by tiny Eibar last week, took a fortuitous lead when Valencia midfielder Daniel Wass nodded a Dani Carvajal cross into his own net in the eighth minute after former Arsenal defender Gabriel Paulista had failed to clear the danger.
Chelsea banished any fears of a repeat of last season's shock FA Cup fourth-round exit to Bradford City when they crushed Championship (second-tier) side Milton Keynes Dons 5-1 away to reach the fifth round on Sunday.
Real Madrid through to next round, win 6-2 on aggregate, Liverpool ousted
Images from the English Premier League London derby played between Arsenal and Chelsea at the Emirates on Wednesday
Vinicius Jr came off the bench to score once and set up another goal to steer champions Real Madrid to a 4-1 fightback victory over Espanyol.
World champions France had eight players, one less than former holders Spain, in international players' association FIFPro's 55-name shortlist for its World XI of 2018 award.
A second half double from Karim Benzema helped Real Madrid to a 4-1 victory at Girona on Sunday and maintain their perfect La Liga start in the post-Cristiano Ronaldo era.
Tuesday's semi-final in St Petersburg sees team mates from English champions Manchester City, Chelsea, Manchester United and Tottenham Hotspur go head to head as well as rivalries between club colleagues from Barcelona, Paris St Germain and Monaco.
Belgium coach Roberto Martinez declared himself delighted with a 3-0 win over World Cup debutants Panama but there were plenty of issues that will encourage England after their own winning start in Group G.
A summary of Saturday's action in the Euro 2024 qualifying matches.
Finland, who came third with three points, must wait until the end of the group stage to see if their adventure in a first ever major tournament will continue and they need a series of results to go their way if they are to make the last 16.
Chelsea manager Jose Mourinho has joked that he might make a bid to sign Liverpool captain Steven Gerrard on loan when he leaves for the United States at the end of the season.
Antonio Conte's return to Italian football on Tuesday proved such a chastening experience as he watched his Chelsea side dismantled by AS Roma in the Champions League that he worries they could be set for a "very difficult" season.
A superbly-executed strategy by coach Antonio Conte helped Italy to a deserved 2-0 win over Belgium in their Euro 2016 opener with outstanding goals by Emanuele Giaccherini and Graziano Pelle on Monday.
